Showing 292 open source projects for "c:\program files\micronetics\msmws\program\"

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  • 1

    denovo_hit

    Outputs potential denovo variants from VCF given pedigree information.

    Program takes variants calls and determines if the call is novel for a child compared to parents. Program can handle both annotated and unannotated VCF files, however output file is not compatible with GATK's snpEff, so you should annotate prior to using denovo_hit. Usage: ./denovo_hit <VCF file> <PED file> Output: ./potential_denovo.txt To compile: g++ -std=c++11 denovo_hit.cpp -o denovo_hit Please see files for example VCF file, and pedigree file. ...
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  • 2

    REDO

    REDO - RNA Editing Detection in Organelle

    REDO is a comprehensive application tool for identifying RNA editing events in organelles based on variant call results (VCF files). It is a suite of Perl scripts and can work easily and directly in any operating system installed Perl and R Environment. The stringent rule depended filters and statistical filters are used in REDO for reducing false positive rate. It can provide detailed annotations, statistics and figures for RNA editing sites. REDO also can detect RNA editing events in...
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  • 3

    RGAAT

    Reference based genome assembly and annotation for new genome

    This program can assemble and/or annotate genome for new genome and known genome upgrade using sequence alignment file (SAM or BAM format), sequence variant file (VCF format or five coloum table (tab-delimited, including chromosome, position, id, reference allele and alternative allele)) or new genome sequence file (FASTA format) based on reference genome sequence file (FASTA format) and annotation file (TBL, GTF, GFF, GFF3 or BED format).
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  • 4
    The Systems Biology Results Markup Language is a language describing data. Unlike flat data formats, SBRML allows describing the origin of the data as well. This project hosts a library and tools for using SBRML.
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  • 5

    skewer

    A fast and sensitive adapter trimmer for illumina paired-end sequences

    This program implements a novel dynamic programming algorithm dedicated to the task of adapter trimming and it is specially designed for processing illumina paired-end sequences.
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    Downloads: 5 This Week
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  • 6

    fast_count_multi

    Extremely fast NGS read counter

    Counts NGS read alignments against GTF annotations in a multithreaded and scalable fashion. Benchmark: 8 core 1M annotations for 2Gb sorted reads ~30 seconds compared to ~28 minutes for bedtools multicov. Files include: fast_count_multi - reports all counts and RPKM, multithreading support fast_count_deseq - reports gene counts in deseq compatible format, multithreading support fast_count - reports all counts with no multithreading support. usage ./fast_count_multi num_threads gtf_file bam_file(s) > output Requires bamtools API library at run time, and c++0x for compile. ...
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  • 7

    CRISPR-Offinder

    a CRISPR guide RNA design and off-target searching to

    ...Therefore, there is an urgent need to develop a versatile tool to design sgRNA to satisfy the requirement of different RNA-guided DNA endonucleases. To this end, a flexible sgRNA design program named “CRISPR-offinder” was developed. The most important feature of this new program is that it supports all known PAM types, as well as the customer-defined PAM. Besides, CRISPR-offinder can find and rank the candidate sgRNAs in genome by off-target sites number, and also can be used to design single or paired-gRNAs. CRISPR-offinder is freely available as a command-line program or accessible via our website. ...
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  • 8

    biosbl

    Standard Bioinformatics Library

    set of classes used to handle input/outputs of bioinformatics data files and basic operations as multiple alignment and phylogenetic reconstruction.
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  • 9
    olego

    olego

    OLego – short or long RNA-seq read mapping to discover exon junction

    ...It is implemented in C++ with full support of multiple threading, to allow fast processing of large-scale data.
    Downloads: 0 This Week
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  • 10
    iMSAT
    iMSAT represents a full update of the vcf2MSAT program. This command line python program allows for a user to use the polymorphism data generated using SAM- and BAM-tools and a .fasta alignment file to search for polymorphic microsatellite markers (MSATs or STRs). By identifying polymorphic makers, rather than simple repeat regions as previous programs have done, iMSAT greatly increases the speed at which polymorphic MSATs that can be identified -- saving researchers precious time and money. ...
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  • 11
    PANorama2.0

    PANorama2.0

    PANorama: Panicle phenotyping for Oryza sativa

    PANorama is a Linux-compatible, open-source software package for panicle image acquisition, processing, and phenotyping. PANorama 2.0 contains new phenotype measurements and is available for download within the "Files" tab listed above. Installation and user instructions are located within the "Wiki" tab. How to videos are available for streaming at the link below, or for download in the "Files" tab above. Information regarding the project and funding can be found at...
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  • 12
    Flexbar

    Flexbar

    flexible barcode and adapter removal for sequencing platforms

    Flexbar moved to https://github.com/seqan/flexbar The program Flexbar processes high-throughput sequencing data efficiently. It demultiplexes barcoded runs and removes adapter sequences. Moreover, trimming and filtering features are provided. Flexbar supports next-generation sequencing data in fasta and fastq format, e.g. from the Illumina platform. Reference: Matthias Dodt, Johannes T.
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  • 13

    Madeline 2.0 Pedigree Drawing Engine

    Madeline 2.0 Pedigree Drawing Engine (PDE)

    The Madeline 2.0 Pedigree Drawing Engine is a pedigree drawing program designed to handle large and complex pedigrees with an emphasis on readability and aesthetics. PLEASE NOTE THAT as of 2015.09.30, the most current Madeline source code tree is now maintained on GITHUB at https://github.com/piratical/Madeline_2.0_PDE .
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  • 14
    TinkerCell is a software for synthetic biology. The visual interface allows users to design networks using various biological "parts". Models can include modules and multiple cells. Users can program new functions using C or Python. www.tinkercell.
    Downloads: 34 This Week
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  • 15
    vcftools
    A set of tools for working with VCF files, such as those generated by the 1000 Genomes Project. This project is migrating to github: https://vcftools.github.io/
    Downloads: 31 This Week
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  • 16
    FMFilter

    FMFilter

    Fast Model Based Variant Filtering Tool

    Filtering out the prominent portion through the excessive amount of information produced by next generation techniques is a challenging task. Current tools enable to analyze next generation sequencing data in various methods. However, there is still need for fast, easy to use and efficacious tools. We provide an efficient filtering tool for next generation sequencing data produced by genetic disease studies. FMFilter allows to choose one of the inheritance models (recessive, dominant,...
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  • 17

    MDA

    Molecular Dynamics Analyzer (MDA)

    ...It does not require additional experimental effort for the user and imaging can directly be started once interesting regions in the sample have been identified. MDA is written in MATLAB and comes with a graphical user interface. The particle fitting routine is provided by an external library written in C. The results can be exported into the Matlab Workspace or the trackID, frameID and xyz coordinates are saved into files.
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  • 18

    detectIR

    Detection of Perfect and Imperfect Inverted Repeats

    detectIR - a MATLAB-based tool for detecting perfect and imperfect inverted repeats in genomes. [1] Who are we? Please visit website: http://bioinfolab.miamioh.edu [2] How to cite detectIR? Ye C, Ji G, Li L, Liang C (2014) detectIR: A Novel Program for Detecting Perfect and Imperfect Inverted Repeats Using Complex Numbers and Vector Calculation. PLoS ONE 9(11): e113349. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113349 [3] detectIR user manual Please visit the Wiki page of this website. [4] detectIR Q&A For Q&A, please visit the Blog page of this website...
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  • 19

    Virus QSP Modeling

    C++ and Python code for simulating RNA virus replication

    Stochastic simulation model of poliovirus Sabin-to-Mahoney genetic state transition (C++ code). Models genotypes, virus populations, and quasispecies cloud. Simulates replication error and copy-choice recombination. Various parameters guiding the model are user-specified. Python code post-processes simulation output to produce report files.
    Downloads: 1 This Week
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  • 20
    ADOMA
    ...ADOMA uses ClustalW to create the multiple alignment from DNA or protein sequences and displays them slightly different than the normal output of ClustalW. ADOMA is a commandline program that can easily be used in pipelines. For more information check the README.md in the Files section. How to cite ADOMA: Zaal, D. and Nota, B. (2016), ADOMA: A Command Line Tool to Modify ClustalW Multiple Alignment Output. Mol. Inf., 35: 42–44. doi: 10.1002/minf.201500083 http://onlinelibrary.wiley.com/doi/10.1002/minf.201500083/abstract
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  • 21
    Identikit
    A basic and easy java program to make black and white identikit drawing ,with a library of face elements that you can also modify and expand without limit !Source code available. Also available a very rough base for a 3D construction of the face.
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    Downloads: 6 This Week
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  • 22

    GUItars

    GUItars is designed for the analysis of high throughput RNAi data.

    ...GUItars uses SSMD for hit selection, which is preferred for its ability to diminish sample size effects and the false hit rate, making it superior to other widely used HTS analysis methods. The program can handle the analysis for screens without replicates as well as with replicates. For comparison purposes, non-SSMD-based methods such as percent activity, z-score, and t-test are also provided as scoring options. Version 2.1 released: several bugs fixed. Version 3.0 released for Windows and Mac: experiment-wise analysis option, map to all samples option (no hit cut-off needed), percent activity for replicates option and .ai output format are added
    Downloads: 0 This Week
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  • 23
    gMol

    gMol

    gMol molecular graphics

    We've moved to https://github.com/tjod/gMol/wiki gMol is an interactive visualization system used to display and manipulate 3-dimensional models of scientific data, such as molecular structures and surfaces. It contains both OpenGL and web browser widgets that enable flexible user interfaces.
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  • 24
    The Program to Assemble Spliced Alignments (PASA) is used to automatically incorporate ESTs and full-length cDNAs into gene structure annotations, in the process annotating UTRs, alternative splicing variations, and polyadenylation sites.
    Downloads: 0 This Week
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  • 25
    CellCompiler
    The target system of this project is to develop mathematically efficient program code generator from cellml like biological models described by mathematical markup languages.
    Downloads: 0 This Week
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